Can genetic mutations benefit an organism?

Yes

Explanation:

Benefical mutations (mutations that help or benefit an organism) are very important to evolution! They increase an organisms survival or reproduction rates, leading the mutations to spread among the species.

Have a good day :D

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme