Who has to approve the president's appointments?

Under the Appointments Clause of the United States Constitution and law of the United States, certain federal positions appointed by the president of the United States require confirmation (advice and consent) of the United States Senate.

Advice and consent from the United States Senate.

Explanation:

the answer to the blank provided is “an autosomal gene that is required for the expression of genes on the x chromosome”.

testis-determining factor, abbreviated as td, which is more popularly known as sex-determining region y or sry protein, is a dna-binding protein or  gene-regulatory protein/transcription factor, encoded by the  sry gene. it is the gene responsible for the initiation of male gender determination in humans.