What is the role of Cdks? to create enzymes that produce chemical changes to signal the cell to move to the next phase of the cell cycle build structural components of DNA and energy-rich substances to activate the cyclins that cause progression of the cell cycle

to signal the cell to move to the next phase of the cell cycle

Explanation:

(Just took it)

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme