Disease/ SyndromeSymptomsAffected OrganelleNormal Function of Organelle
Cystic FibrosisChokingly thick mucus in the lungs; frequent lung infections; clogged pancreas; digestive problems; salty sweat. Salt has problems leaving and entering the cells of the lungs and pancreas.
Tay-SacsInfant appears normal until the age of 3 to 6 months. Loss of the ability to turn over, crawl and sit up. The disease will affect the nerve cells and infants will become irritable and could have seizures. Unfortunately, blindness, deafness, and paralysis follow. Patients do not usually live past the age of 5. Symptoms result due to the lack of an enzyme to breakdown fatty waste substances in nerve cell.
AchondrogenesisInfant has a small body, short limbs and other skeletal abnormalities. Due to serious health problems infants are stillborn or die soon after birth. Abnormalities are due to proteins not being packaged and moved to the endoplasmic reticulum.
Leigh’s DiseasePeople with this syndrome have trouble with motor control such as, swallowing or sucking, leading to a failure to thrive. This usually occurs after a viral infection. The disease is due to problems with less energy being generated within cells resulting in damage to cells in the liver, heart, brain, skeletal muscles, etc.