Biology
Biology, 10.09.2020 01:01, fansofboys

GPCR activate G proteins by reducing the strength of GDP binding, allowing GDP to disassociate and GTP, which is present at much higher concentrations, to bind. How do you suppose the activity of a G protein would be affected by a mutation that caused its affinity for GDP to be dramatically reduced without changing its affinity for GTP

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GPCR activate G proteins by reducing the strength of GDP binding, allowing GDP to disassociate and G...

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