As the Black Death spread in the mid-14th century, which region tended to experience the greatest loss of life?
A) Urban areas
B) Rural Farms
C) Remote villages
D) Mountainous areas

urban areas

Explanation:

because the population of urban areas in those countries is more then villages.

osteogenesis imperfecta (oi) refers to a congenital ailment of bones. in the condition, the bones become brittle or fragile. this ailment is a general result of the defect or mutations in the genes (colia1 or colia2). this mutation results in imperfect collagen formation either in quantity or quality wise.  

there are eight kinds of oi defects, and each kind varies with certain distinctions in symptoms. the usual symptoms include frequent bone fractures, loss of hearing in infants, protruding eyes, discoloration of the white in the eyes, respiratory issues, loosening of the joints, short stature, and other symptoms.