Many types of cancer are known to overexpress the receptor protein tyrosine kinase. Which molecular technique can be used to reduce expression of tyrosine kinase in cell culture?

By phosphorylation or by activating cyclin-dependent kinase-mediated signaling pathways

Explanation:

The Cyclin-Dependent Kinases (Cdks) are a family of critical regulatory proteins capable of modulating the progression through the cell cycle. Cdks are in turn regulated by binding to cyclin proteins or by phosphorylation at specific amino acid residues (generally tyrosine and threonine).

Phosphorylation is the most widely studied posttranslational modification and it is known to inhibit (and also activate) protein function, while cyclin-dependent kinases are proteins known to inhibit the activity of Cdks and thereby acting as tumor suppressors by inducing cell death-apoptosis.

dna damages cause changes in the structure of the genetic material and prevents the replication mechanism from functioning and performing properly. dna damage and mutation have different biological consequences. while most dna damages can undergo dna repair, such repair is not 100% efficient.

just go with your heart buddy