What role do insulator sequences play in the regulation of eukaryotic transcription? See Section 13.1 (Page 479) . What role do insulator sequences play in the regulation of eukaryotic transcription? See Section 13.1 (Page 479) . They block communication between enhancers and nontargeted promoters. They block binding of transcription factors to enhancers. They block binding of transcription factors to cis-acting promoter elements. They block binding of transcription repressors to cis-acting promoter elements. You have already submitted this answer. Enter a new answer. No credit lost. Try again.

They block communication between enhancers and nontargeted promoters.

Explanation:

Insulator sequences control transcription in multicellular eukaryotes. They are present near the enhancer region of a gene. When required proteins bind to them, they get activated. They interact with the enhancer region and hamper its function. Enhancer sequences increase the rate of transcription by interacting with the promoter region. Insulators block the communication between enhancers and non target promoters by various methods. For example, they can form a loop domain between enhancer and promoter which avoids them form interacting. In this way, transcription is halted.

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