The nose sinuses permits in transit or part of the opera respiratory system

air enters through the nose, moves through the nasal cavity, the pharynx, the larynx, enters the trachea, moves through the bronchi andbronchioles till the alveoli.

some scientists like gregory adcock agree with thorne's theory of regional continuity.

others, like chris stringer and ian tattersall, believe thorne's results may be contaminated or misinterpreted.

osteogenesis imperfecta (oi) refers to a congenital ailment of bones. in the condition, the bones become brittle or fragile. this ailment is a general result of the defect or mutations in the genes (colia1 or colia2). this mutation results in imperfect collagen formation either in quantity or quality wise.  

there are eight kinds of oi defects, and each kind varies with certain distinctions in symptoms. the usual symptoms include frequent bone fractures, loss of hearing in infants, protruding eyes, discoloration of the white in the eyes, respiratory issues, loosening of the joints, short stature, and other symptoms.