Biology, 24.04.2020 22:30, tpsavage9755

Notice that the intermediate in the reaction of citrate synthase is citryl CoA. Suppose evolution produced a strain a bacteria with an altered citrate synthase enzyme that produced citrate and used the energy from breaking the thioester bond to make ATP. After all, other enzymes in metabolism use the energy in thioester bonds to make ATP, and the DG°’ of the citrate synthase reaction is -7.7 kcal/mole (more than enough to cover the +7.3 kcal/mole cost of converting ADP + Pi ® ATP. Explain why such a bacterium would be at a selective disadvantage.

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Notice that the intermediate in the reaction of citrate synthase is citryl CoA. Suppose evolution pr...