Philadelphia Syndrome occurs when the distal segments of chromosome 9 and chromosome 22 are reciprocally translocated. Examine the diagram below. Chromosome 9 is on the left while chromosome 22 is on the right. The areas bounded by the dashed lines are the portions of the chromosomes that are translocated. The labeled black bands on the chromosomes are genes. Note the position of the ABL1 gene on chromosome 9 and the BCR gene and PDGFB gene on chromosome 22.

a. How does the translocation affect the location of the labeled genes? Where does the ABL1 gene end up? Where does the PDGFB gene end up? Draw what the chromosomes would look like after the translocation. Show the correct positions of the ABL1 gene, the BCR gene, and the PDGFB gene. Use the space to the right of the illustration. (2)

b. Philadelphia syndrome results when a hybrid gene is created by the translocation described above. This hybrid gene codes for a signaling protein that causes the cell to divide uncontrollably. Based on what you know about cell cycle control, speculate on how this signaling protein might be responsible for uncontrolled cell division. (3)

increase soil erosion                                             reduce soil erosion

cattle grazing                                                         hydroseeding

deforestation                                                         contour plowing

                                                                                planting vegetation

plant roots basically hold the top soil

together and stop soil erosion because

in such situation top soil is not removed

during flood but cattle grazing causes

soil erosion because cattle consume the

grasses and herbs and top soil is exposed.

same situation occurs because of

deforestation, the trees and plants are cut

down to expose top soil which causes soil

erosion

the framers of the constitution insisted that federal judges be nominated instead of elected due to their desire to have judges above the shifting whims of the masses.

the hope, whether achieved or not, was that federal judges would only be beholden to the law and that by not having judges be elected, they would be protected if that law dictated an outcome that ran counter to popular opinion.