The information in pedigrees that is useful for mapping disease genes is sometimes limited. This pedigree shows segregation of neurofibromatosis, which is a fully-penetrant, autosomal dominant condition, and a single nucleotide polymorphism, SNP1, which has alleles G or T. Why is the cross in generation I not useful for determining the degree of linkage between the disease-causing gene NF and SNP1?

Match the descriptions / definitions with the term they best describe 1. three dimensional relationship of the different polypeptide chains in a multisubunit protein or protein complex 2. common folding pattern in proteins in which a linear sequence of amino acids folds into a right-handed coil stabilized by internal hydrogen-bonding between polypeptide backbone atoms. 3. the amino acid sequence of a protein 4. a region on the surface of a protein that can interact with another molecule through noncovalent bonding. 5. three-dimensional arrangement of alpha-helices and beta-sheets within a single polypeptide, typically stabilized by a variety of noncovalent bonds, including ionic and hydrogen bonds, and nonpolar interactions / hydrophobic force. 6. the chain of repeating carbon and nitrogen atoms, linked by peptide bonds, in a protein. 7. common structural motif in proteins in which different sections of the polypeptide chain run alongside each other and are joined together by hydrogen bonding between atoms of the polypeptide backbone. 8. portion of a polypeptide chain that has a discrete tertiary structure of its own and can often fold independently of the rest of the chain 9. regular local folding patterns in a protein, including alpha-helix and beta-sheet a. primary structure b. beta-sheet c. protein d. coiled-coil e. polypeptide backbone f. secondary structure g. side chain h. tertiary structure i. binding site j. alpha-helix k. quaternary structure l. protein domain

(drag each tile to the correct identify which questions can be answered by what can be answered by science or which cannot. -is it right or wrong to use genetic engineering to produce new food products? -what are the most common social settings that tend to produce accomplished artists? -if a new gene is added to the genome of a tomato species, will that species be more resistant to insects? -should humans use biotechnology to bring extinct organisms from the fossil record back to life? -do the types of organisms found in the fossil record appear in consistent sequences in different parts of the world? -are michelangelo's paintings more impressive than rembrandt's?

What is the name of the type of cell division that occurs in the prokaryotic cell cycle