Matings between individuals from the two populations of Rhagoletis produce hybrid flies that appear to be healthy and have normal life spans. The eggs laid by these hybrid flies, however, hatch less often than those of flies from either of the two populations. What isolating mechanism seems to be important in this hybrid population?

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multiple allele inheritance is traits controlled by more than 2 alleles (ex: pigeons having 3 alleles of one gene govern their feather color).   so the answer is a.