Here are a list of events that involve changes to genotype and phenotype. Arrange these events in sequential order, from first to last.
The altered gene is transcribed into mRNA.
The sequence of nucleotides changes in a gene.
The sequence of amino acids is altered in a protein.
The function of the protein is altered, affecting phenotype.

The sequence of nucleotides changes in a gene.

The altered gene is transcribed into mRNA.

The sequence of amino acids is altered in a protein.

The function of the protein is altered, affecting phenotype.

Explanation:

To see a change in a phenotype, the negative change (mutation) should occur in the gene first. Neutral mutations would not lead to a change in phenotype because it doesn't change the type of amino acid essentially. This means that, the first step would be the change in the gene itself. Then, the gene would be translated to mRNA. Then, the mRNA will instruct ribosomes to make an altered protein. Finally, the expression of protein due to different amino acid would lead to a different phenotype.

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