In a humoral or antibody-mediated immune response, specific B cells are stimulated by Helper T cells to help transform into plasma cells that secrete antibodies. What would be an important feature added to B cells in the transition process?

A. Increased rough endoplasmic reticulum in order to have the surface area needed for antibody production
B. Duplication of specific gene sequences for the appropriate antibody.
C. Duplication of lysosomes in order to store the antibodies before transport.

An important feature that B-cells must have in order to become plasma cells and synthesize antibodies is increased rough endoplasmic reticulum in order to have the surface area needed for antibody production (option A).

Explanation:

The transformation of B cells into plasma cells to produce antibodies is a well known function of lymphocytes related to the immune response. This leads to a series of structural transformations in order to performs their function.

The rough endoplasmic reticulum (RER) has the function of contributing to protein synthesis, in conjunction with the ribosomes that are attached to it and the information of the mRNA.

One of the changes experienced by B cells in their transition to plasma cells is the availability of larger RERs, in preparation for antibody synthesis, formed mostly by proteins.

Learn more:

Plasma cells and humoral immune response link

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