Metastatic cancer cells: a) have lost their adhesion to the extracellular matrix, freeing them from the original tumor. b) are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites. c) only need to cross a single layer of capillary endothelial cells to form tumors at distant sites. d) all of these choices are correct. e) become malignant when they grow rapidly.

Only option b) is correct

Explanation:

Metastasis is the the property of cancerous cells

Metastasis is the migration of cancerous cells from one place to another place thus spread cancer in different locationsCancer cells loose the property of contact inhibition growth(adhesion property):after proper contact with neighbouring cells/tissues cell division is blocked in normal cell but not cancer cellMalignancy is the very fast rate of growth and division of cancerous cellsAll the given choices are properties of cancerous cells but metastasis property is described by option b) only

The answer will be d