Cyclin B1, a key cell cycle regulatory protein in vertebrates, is mostly cytosolic before mitosis. Early in mitosis, however, the protein is phosphorylated by certain protein kinases and consequently accumulates in the nucleus. How can phosphorylation bring about nuclear accumulation of this protein?
A. Phosphorylation within the nuclear localization signal inhibits the function of the signal.
B. Phosphorylation within the nuclear export signal enhances the function of the signal.
C. Phosphorylation within the nuclear export signal interferes with the function of the signal.
D. Phosphorylation elsewhere on the protein enhances binding to cytosolic proteins

the elements of art are the visual tools that the artist uses to create a composition. these are line, shape, color, value, form, texture, and space.

the principles of art and design are balance, contrast, emphasis, movement, pattern, rhythm, and unity/variety.

interphase

the period of cell growth when the cell synthesizes new molecules and organelles. the cell is not dividing and it constitutes the majority of the time spent in the cell cycle

prophase

changes occur in the nucleus and cytoplasm. the chromatin condenses to form structures (sister chromatids) visible with a light microscope and the mitotic spindle begins to form, but the nucleus is still in tact

prometaphase

the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the sister chromatids

metaphase

all the cell's duplicated chromosomes are lined up at an imaginary plane equidistant between the poles of the mitotic spindle

anaphase

begins when sister chromatids separate from each other and ending when a complete set of daughter chromosomes arrives at each of the two poles of the cell

telophase

the daughter nuclei form at the two poles of a cell

cytokinesis

the division of a cytoplasm to form two separate daughter cells. usually occurs during telophase during mitosis. this and mitosis make up to mitotic (m) phase of the cell cycle