As filtrate passes through the long loop of Henle, salt is removed and concentrated in the interstitial fluid of the kidney medulla. Because of this high salt concentration, the nephron is able to .

Nephron is the functional unit of kidney. The kidney contains around 4 to 5 million of nephrons in their structure. These nephrons helps in the blood filtration.

The loop of Henley passes down the filtrate for the production of urine. The excess salt is removed from the loop and deposited in the medullary part of the kidney. This is important as the nephron can now become hyperosmotic  medullary concentration and helps in the urine production.

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