Three commonly used tests for carpal tunnel syndrome are tinel’s sign, phalen’s test, and the nerve conduction velocity test. tinel’s sign and phalen’s test are both highly sensitive (0.97 and 0.92, respectively) and specific (0.91 and 0.88, respectively). the sensitivity and specificity of the nerve conduction velocity test are 0.93 and 0.87, respectively.
assume that the tests are conditionally independent.
calculate the sensitivity and specificity of a combined test if combining is done:
(a) in a serial manner;
(b) in a parallel manner.
(c) find positive predictive value (ppv) for tests in (a) and (b) if the prevalence of carpal tunnel syndrome in the general population is approximately 50 cases per 1000 subjects.
tests are combined in a serial manner if the combination is declared positive when all tests are positive.
tests are combined in a parallel manner if the combination is declared positive when at least one test is positive.

Match the descriptions / definitions with the term they best describe 1. three dimensional relationship of the different polypeptide chains in a multisubunit protein or protein complex 2. common folding pattern in proteins in which a linear sequence of amino acids folds into a right-handed coil stabilized by internal hydrogen-bonding between polypeptide backbone atoms. 3. the amino acid sequence of a protein 4. a region on the surface of a protein that can interact with another molecule through noncovalent bonding. 5. three-dimensional arrangement of alpha-helices and beta-sheets within a single polypeptide, typically stabilized by a variety of noncovalent bonds, including ionic and hydrogen bonds, and nonpolar interactions / hydrophobic force. 6. the chain of repeating carbon and nitrogen atoms, linked by peptide bonds, in a protein. 7. common structural motif in proteins in which different sections of the polypeptide chain run alongside each other and are joined together by hydrogen bonding between atoms of the polypeptide backbone. 8. portion of a polypeptide chain that has a discrete tertiary structure of its own and can often fold independently of the rest of the chain 9. regular local folding patterns in a protein, including alpha-helix and beta-sheet a. primary structure b. beta-sheet c. protein d. coiled-coil e. polypeptide backbone f. secondary structure g. side chain h. tertiary structure i. binding site j. alpha-helix k. quaternary structure l. protein domain

Which muscle is responsible for inhalation ?

Jane is blood type a her husband is blood type b. jane is puzzled because their daughter is type o. explain how the daughter inherited a blood type that neither of her parents had explain your answer