Which statement about enzymes is false? select one: a. enzymes may be damaged by high temperature. b. most enzymes can catalyze millions of reactions per minute. c. enzymes require contact with substrate in order to assume their active form. d. enzymes may use coenzymes derived from vitamins or cofactors from metallic elements.

(C) Enzyme does not need to contact with substrate to assume its active form.

Explanation:

a) The activity of an enzyme can be increased upto certain temperature known as optimum temperature after that tepmerature will damage the enzyme.

b) The number of substrate molecule converted by one molecule of enzyme in one second is called its turn over rate, which may varry from 0.5-600000.

C)  Enzymes does not need to contact with substrate to assume its active form. They just accelerate the reaction by lowering the activation energy. Enzyme binds to substrate through active stite and both changes structures slightly to best fit.(Induce fit  model)

D) Some enzymes are inactive known as apoenzyme and they need a non-protein part such as coenzyme or cofactor to become active which is known as holoenzyme.