Why do you think abnormally folded
hemoglobin would make it harder for the
protein to carry oxygen?

Answer AND Explanation:

When the hemoglobin is folded, there is less surface area for transportation and binding of oxygen. The oxygen binds poorly leading to anaemia. The oxygen is transported by haemoglobin in form of oxyhaemoglobin to the tissues.

when you breathe in, or inhale, your diaphragm contracts (tightens) and moves downward. this increases the space in your chest cavity, into which your lungs expand. the intercostal muscles between your ribs also enlarge the chest cavity. they contract to pull your rib cage both upward and outward when you inhale.