In class we also talked about the metabolism of hdl particles.

a. the metabolism of hdl involves the formation of immature hdl particles in the liver.
b. these immature hdl particles (nascent hdl) contain only a small amount of cholesterol and no cholesteryl esters.
c. as hdl particles circulate through the bloodstream, they are transformed into mature hdl particles by picking up extra cholesterol from cholesterol-rich extrahepatic cells.
d. this process is called reverse cholesterol transport.
e. the number of mature hdl particles in circulation is inversely proportional to cardiovascular disease and atherosclerosis.
describe the basis of this inverse relationship.