Giulia mcgettigan was born full term with a malformed jaw, cleft palate, a ventricular septal defect, and hypocalcemia. within 48 hours of birth she developed muscle tetany, convulsions, tachypnea, and a systolic murmur. a chest x-ray showed an enlarged heart and the absence of a thymic shadow. blood tests showed severely depleted levels of cd4 and cd8 t cells; b-cell numbers were low but within normal range. parathyroid hormone was undetectable. fluorescence in situhybridization of the buccal mucosa revealed a small deletion in the long armof chromosome 22. giulia failed to thrive and battled chronic diarrhea and opportunistic infections, including oral candidiasis and pneumocystis jirovecii, the latter infection causing her death. giulia most probably had which of the following immunodeficiency diseases?

a. aids
b. digeorge syndrome
c. bare lymphocyte syndrome
d. chronic granulomatous disease
e. hyper igm syndrome.

interphase

the period of cell growth when the cell synthesizes new molecules and organelles. the cell is not dividing and it constitutes the majority of the time spent in the cell cycle

prophase

changes occur in the nucleus and cytoplasm. the chromatin condenses to form structures (sister chromatids) visible with a light microscope and the mitotic spindle begins to form, but the nucleus is still in tact

prometaphase

the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the sister chromatids

metaphase

all the cell's duplicated chromosomes are lined up at an imaginary plane equidistant between the poles of the mitotic spindle

anaphase

begins when sister chromatids separate from each other and ending when a complete set of daughter chromosomes arrives at each of the two poles of the cell

telophase

the daughter nuclei form at the two poles of a cell

cytokinesis

the division of a cytoplasm to form two separate daughter cells. usually occurs during telophase during mitosis. this and mitosis make up to mitotic (m) phase of the cell cycle