Salmonella typhimurium is a food-borne bacterial pathogen that can cause severe gastrointestinal disease. salmonella is often phagocytosed by macrophages that normally destroy bacterial pathogens, but this bacterium is somehow able to prevent the complete maturation of phagolysosomes. salmonella is able to tolerate the low ph of phagolysosomes, and in fact responds to the drop in ph by secreting toxins that interfere with other cellular responses. which of the following differences would you expect to contribute to the survival of a bacterium within an salmonella-containing phagosome, compared to a healthy phagolysosome?

The correct option is decreased activity of acid hydrolases.

Explanation:

Phagolysosomes play an effective role in generating front line defence against bacterial infections. They contain enzymes such as acidic hydrolases enzymes which are involved in generating an immune response. Hence, if Salmonella affects the maturation of phagolysosomes, then the acid hydrolases will not be able to form. The activity of the acid hydrolases will deplete which will cause serious issues in immunity. The health of the person will get affected.

explanation:

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