Genetic and chemical modifications are often performed on antimicrobial drugs. which of the following statements explains the advantage of performing such drug modifications? to be marked correct, you'll need to select all applicable statements, as there may be more than one correct answer.

a. chemical modification may allow for extended drug capacities such as expanded spectrum of activity and increased stability.
b. natural antibiotics are rare in nature, so one must rely on chemical drug synthesis of drugs.
c. chemical editing may allow for enhanced drug production.
d. chemical modifications can allow for certain antimicrobial resistance mechanisms to be circumvented.

A. Chemical modification may allow for extended drug capacities such as expanded spectrum of activity and increased stability.

Explanation:

Any modification in antibiotic structure and chemical will affects its ability in a way to increase it capability of target microbes and act efficiently. These modification can increase half life and stability of the drug.  

step 1: nitrogen fixation- conversion of atmospheric no₂ into forms useful to plants by lightning, bacteria, and cyanobacteria.

step 2: nitrification-process of converting ammonia to nitrite or nitrate.

step 3: assimilation-plant roots absorb new form of nitrogen.

step 4: ammonification-conversion of organic nitrogen to ammonia by bacteria involved in decomposition.

step 5: denitrification-bacteria turns the decomposed matter back into n₂o, which is released into atmosphere; repeat cycle.