Oxygen shows cooperative binding to hemoglobin. cooperative binding has the following effects on the binding and release of oxygen:
oxygen binding to hemoglobin: when one molecule of oxygen binds to one of hemoglobin's four subunits, the other subunits change shape slightly, increasing their affinity for oxygen.
oxygen release from hemoglobin: when four oxygen molecules are bound to hemoglobin's subunits and one subunit releases its oxygen, the other three subunits change shape again. this causes them to release their oxygen more readily.
these two graphs show how cooperative binding differs from a hypothetical situation where binding is not cooperative.
the x-axis shows the partial pressure of oxygen (po2). this is a measure of the amount of oxygen present in a tissue. the blue arrows on the x-axis show the partial pressure of oxygen in various tissues of the body.
the y-axis shows the oxygen saturation of hemoglobin (o2 saturation). this is the percentage of oxygen-binding sites on hemoglobin molecules that are actually bound to oxygen.

When four oxygen molecules are bound to hemoglobin's subunits and one subunit releases its oxygen, the other three subunits change shape again. This causes them to release their oxygen more readily.

Explanation:

Each hemoglobin molecule can bind up fou oxygen molecules, hemoglobin exhibits what it is call cooperative binding, as oxygen binding increases the affinity of hemoglobin for more oxygen. Incresed affinity is caused by a conformational change, or structural change in the hemoglobin molecule.

The cooperative binding of oxygen to hemoglobin is an important adaptation for gas exchange . Cooperativity allows hemoglobin to release much more oxygen to our body's tissues.

this protocol provides a detailed procedure for co-immunoprecipitation (co-ip) to identify protein–protein interactions.

answer : haversian

[explanation: -(compact bone is organized as parallel columns, known as haversian systems, which run lengthwise down the axis of long bones. these columns are composed of lamellae, concentric rings of bone, surrounding a central channel, or haversian canal, that contains the nerves, blood vessels, and lymphatic system of the bone)]