What is the difference between a gene rearrangement and a gene alteration?

In genetics, a chromosomal rearrangement is a mutation that is a type of chromosome abnormality involving a change in the structure of the native chromosome. Such changes may involve several different classes of events, like deletions, duplications, inversions, and translocations.

Explanation:

from the original order (top to bottom) the new order will go

1 (founder)

4 (hawk)

2 (mutate)

3 (next generation)