Which of the following resistance mechanisms is the most nonspecific to a particular class of antimicrobials?
drug modification
target mimicry
target modification
efflux pump

The efflux pump is the most nonspecific to a particular class of antimicrobials.

Explanation:

Antimicrobial -

An antimicrobial , the agent which destroys or kills the microorganism or inhibits their growth .

And these microbes can even develop resistance mechanism which involves the inhibiting the accumulation of the antimicrobial drug .

This is very common among the gram - negative pathogens and hence , involve changes in the outer lipid membrane composition , porin channel concentration and porin channel selectivity .

The gram - negative and gram - positive pathogens bacteria produces efflux pumps that can actively transport the drug out of the cell and thereby prevents the accumulation of the the drug .

tsd is temerature dependent sex determination.

tsd: it is a type of environmental sex determination in which the temperature experienced during embryonic/ larval development (ambient temperature for development) determine the sex of the offspring.

crocodile displays the tsd where the ambient temperature of the developing egg determines the individual's sex. for example in the american alligator's eggs, incubation at 33 ºc produces mostly males, while incubation at 30 ºc produces mostly females. so if the american alligator's egg will get the ambient temperature (33 degree celcius)during embryonic development from egg, the offspring will be male and same for the female sex determination.

the correct answer, according to e2020, is the second choice there is an occluded front in region a and a cold front in region b.