Ascientist notices that a cancer cell line fails to die when he adds an inducer of apoptosis to his culture of cells. which hypothesis could explain why the cells fail to die?
the cells have a mutation that prevents the initiation of apoptosis signaling.
the cells have lost expression of the receptor for the apoptosis-inducing ligand.
the cells overexpress a growth factor pathway that inhibits apoptosis.
all of the above.

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explanation:

plate tectonics and volcanic euptions

over time, plate tectonic processes cause continents to move to different positions on the globe.

for example, britain was near to the equator 300 million years ago, and therefore was hotter than it is today. for further details look at our climate through time poster or online map.

the movement of the plates also causes volcanoes and mountains to form and these too can contribute to a change in climate.

mountain ranges formed by plate tectonics. large mountain chains can influence the circulation of air around the globe, and consequently influence the climate.   warm air might be deflected somewhere cooler by the mountains.

more words for this could be abiotic and biotic

abiotic: living organisms within an ecosystem

biotic: non-living organisms within an ecosystem