The most common way for a mutation to contribute to disease is by increasing the rate of dna replication directing the formation of altered proteins or unexpected amounts of proteins interfering with the body's immune response silencing the gene containing the mutation. what is common way for a mutation?

A gene mutation refers to a permanent change in the sequence of DNA, which forms a gene, that is, the sequence varies from what is witnessed in the majority of the individuals. The mutations vary in size, they can influence anywhere from a base pair to a huge section of a chromosome, which comprises multiple genes.  

The mutations result in extreme modifications in a species if they modify the manner in which a protein functions. However, a mutation, which directs the formation of altered proteins or the unexpected amounts of proteins is the most general way by which a mutation contributes to disease.