What is the importance of exosome isolation and purification? any would be appreciated. in advance!

As we know that exosomes are small endosome derived lipid nanoparticles (50-120 nm in diameter) secreted into extracellular space by most types of cells. Besides lipids, exosomal content also includes genomic DNA, RNA, proteins which is of great importance. There is cumulative evidence has suggested that exosomes have performed may biological functions particularly in cell-cell communication. More importantly, some exosomes associated proteins and microRNAs are closely related with the pathogenesis of most human diseases by serving as invaluable biomarkers for disease diagnosis, prognosis, and therapy. In order to facilitate the understanding of exosomes biological function and therapeutic application, it becomes crucial to specifically isolate exosomes from a wide spectrum of cellular debris and interfering components, then prepare a highly defined population of exosomes in therapeutic scale by appropriate purification skills.

Explanation:

https://www.creative-biostructure.com/exosome-isolation-and-purification-650.htm

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