Noncompetitive, enzyme, irreversible, acetylcholinesterase, competitive, active site.1. insecticides and nerve gases act as irreversible inhibitors of an enzyme needed for nerve conduction. 2. a inhibitor has a structure that is so similar to the substrate that it can bond to the enzyme just like the substrate. 3. the competitive inhibitor competes with the substrate for the on the enzyme. 4. when the noncompetitive inhibitor is bonded to the enzyme, the shape of the is distorted. 5. a inhibitor binds to a site on the enzyme that is not the active site. 6. usually, an inhibitor forms a covalent bond with an amino acid side group within the active site, which prevents the substrate from entering the active site or prevents catalytic activity.