Choose two genetic disorders and tell how they are inherited

1. Two examples of genetic disorders are CYSTIC FIBROSIS AND SICKLE CELL ANEMIA.

CYSTIC FIBROSIS

Cystic fibrosis is typically inherited when a defect occur in the CFTR gene of an individual. The CFTR gene is responsible for production of a protein that regulates the movement of water and salts out of the body cells. This gene does not perform optimally in people who have cystic fibrosis and this leads to the production of thick, sticky mucus and extremely salty sweat. Individuals who have this disease usually inherit two copies of the defective gene, one from the father and the other one from the mother.

2. SICKLE CELL ANEMIA

Sickle cell anemia is a genetic disorder of the blood, which is cause by inheritance of two copies of abnormal hemoglobin from parents. The hemoglobin is responsible for movement of oxygen all through the human circulatory system. The abnormal hemoglobin causes defective red blood cells, which can not move oxygen around efficiently. Thus, individuals with this disease do not usually get enough oxygen in their blood, this leads to fatigue and chronic pains plus several other negative medical conditions.

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