Is the binding of a transcription factor to its dna recognition sequence necessary and sufficient for an initiation of transcription at a regulated gene?

Transcription factors are necessary for an initiation of transcription at a regulated gene but not sufficient.

Transcription is the first step of gene expression in which DNA molecule is copied (transcribed) into RNA (mRNA) by RNA polymerase. The process of transcription is divided into three phases:

1.Initiation

•RNA polymerase with transcriptional factors bind to gene promoter Transcription factors can enhance the interaction between RNA polymerase and a DNA sequence- promoter, encouraging the expression of the gene. Such transcription factors are called activators. Otherwise, when the gene expression is inhibited, factors are called repressors and they bind to sequence –operator.

•RNA polymerase unwinds DNA double helix (transcription bubble is formed)

2.Elongation

•RNA polymerases adds nucleotides complementary to DNA  

3.Termination

•RNA polymerase gets to stop codon (transcribes a sequence of DNA known as a terminator)

•Formed complementary RNA strand is released from DNA-RNA complex

we would need to see the picture to answer it

imagine a line passing through the center of earth that goes through both the north pole and the south pole. this imaginary line is called an axis. earth spins around its axis, just as a top spins around its spindle. this spinning movement is called earth's rotation. at the same time that the earth spins on its axis, it also orbits, or revolves around the sun. this movement is called revolution.