Why must the structures (organelles) inside a cell be close to the cell membrane?

Within the nucleus is a small subspace known as the nucleolus. It is not bound by a membrane, so it is not an organelle. This space forms near the part of DNA with instructions for making ribosomes, the molecules responsible for making proteins. ... The cell membrane is represented as the "factory walls." (Found on Khan Academy)

the level of progesterone is low at the pre-ovulatory phase of the cycle but it gradually increases and the levels are high at the luteal phase. if pregnancy occurs, the level of progesterone will be high throughout the pregnancy.

if egg is fertilized and the mother gets pregnant, progesterone starts preparing the uterus for the implantation. it starts building up the lining of uterus and make it hostile of the period of pregnancy.

energy and particles