You suspect that a serious developmental disorder is due to a chromosome abnormality and prepare a karyotype from an affected individual. in analyzing the karyotype, how could you distinguish trisomy from a chromosome structural defect such as a duplication?
the chromosome number in trisomy would be normal; in a duplication, there would be one more chromosome.
in both cases there would be an extra chromosome, but in trisomy there would be three chromatids on one chromosome and in a duplication there would be two chromatids on one chromosome.
in trisomy there would be one extra chromosome; in a duplication, the number of chromosomes would be normal, but one chromosome would have two copies of a portion of the chromosome.
the chromosome number in both cases would be normal, but in trisomy there would be three chromatids on one chromosome and in a duplication there would be two chromatids on one chromosome.
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