Analysis ouestions:
use the back of this sheet if you need more room for your answers
1. explain the inheritance pattern of the ear lobe attachment trait. explain bow you determined this.
2. explain the two inheritance patterns of blood type.
3. what did you determine joseph's blood type to be? include genotype and phenotype. explain how you
determined this, including pumnett squares to support your reasoning

1. The shape of the earlobe is determined by a single autosomal gene, with two alleles: the dominant allele (F) expresses a detached (or free-hangning) earlobe, whereas the recessive allele (f) determines an attached earlobe. The potential dominant/recessive combinantions can yield different patterns of inheritance depending on what the allele combination is present in the progenitors (e.g. if both parents are FF, 100% of the progeny will be FF and presenting free earlobes; if one parent is Ff and the other is ff, then the inheritance pattern will be 50% free earlobes 50% attached earlobes.

2. Like the earlobe trait, the inheritance pattern of blood type depends on the combination of alleles, in this case THREE: A, B, and O. A and B are dominant, O is recessive. The Rh factor is determined by the presence (Rh+) or absence (Rh-) of a particular gene (RHD), and is independent from blood type.

3. Joseph's blood Rh factor is +, and his blood type is

Explanation:

1. This is a case of simple Mendelian inheritance. During meiosis, each chromosome will take with it one copy of the allele (e.g., in an individual with Ff genes, one gamete will end up carrying F, the other will end up carrying f). Since this sorting out of alleles is random, there is a random chance that either an F carrying gamete or an f carrying gamete to fuse with a gamete of the opposite gender (carrying in time F or f) to produce the zygote. A Punnett square can be used to show the resulting probabilities (see Question 3).

2. In this case we have two different types of patterns. One given by three allele versions of the same gene, A, B (the dominants), and O, resulting in types A (alleles AA or AO), B (BB or BO), AB (both AB alleles present) and O (OO). The blood type depends on a series of antigens expressed in the cellular membrane, with O alleles expressing none. In the case of the Rh factor, it is inherited independently from blood type as it is coded in a different gene.

3. Joseph's blood factor is Rh+ as some of his progeny with an Rh- partner is Rh +. His blood type is BO, since, even though none of Joseph and Rita's sons or daughters is blood type O, one of their daughters (A type) married a B type and had an O type son. This means that both parents had to have an recessive O allele masked by the dominant allele. Claire has to have inherited this O allele from Joseph as Rita is blood type AB. Punnett square below illustrates this

                                  Joseph

                        B                         O

Rita       A         AB                     AO

             B         BB                      BO

this explains all four blood types from their progeny, with genotypes AO and BO yielding A and B blood types respectively.

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