Write at least four paragraphs on relationship of circulation and integumentary systems

In the skin, the dermis and hypodermis are richly vascularized by a highly structured blood network of medium and small arterioles, capillaries and venules. Conversely, the epidermis, like any epithelium, is not vascularized; it is nourished by imbibition from the capillary networks of the dermal papillae. Similarly, the lymphatic system is present in the dermis and hypodermis and absent from the epidermis.

In the deep part of the hypodermis, the arteries approach the integument and form a first anastomotic network parallel to the cutaneous surface from which perpendicular branches depart that cross the hypoderm, giving collaterals intended to vascularize the fatty lobules and the appendages: sweat glands and hair follicles. These branches meet in the deep part of the reticular dermis to form a second anastomotic network whose meshes are parallel to the first anastomotic network and the cutaneous surface. From this second anastomotic network, perpendicularly leave arterioles called "arterioles in candelabra" leaving branches for cutaneous appendages and the reticular dermis and eventually anastomosing into a third network located at the junction dermal papilla-dermal reticular. From this last network, leave capillaries that win the dermal taste buds. The venous network is modeled on the arterial model. Arteriovenous anastomoses with or without glomus are found at the nail bed and palmoplantar regions (hands, fingers, feet and toes). They play a fundamental role in thermoregulation.

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