The first significant supporting evidence for a biological cause of a mental disorder was the 19th century discovery that the psychotic disorder called general paresis was caused by the same bacterial microorganism that causes

Answer

               The first significant supporting evidence for a biological cause of a mental disorder was the 19th century discovery that the psychotic disorder called general paresis was caused by the same bacterial microorganism that causes syphilis.

Syphilis

           Syphilis is caused by bacteria “Treponema pallidum”. This bacteria cause infection when enter through broken skin of mucus membrane of genitals. It is sexually transmitted disease.  

General paresis

              When syphilis is untreated it lead to damaging of brain and cause a disease called general paresis in which mental activity become dysfunctional. The syphilis bacteria generally attack on brain and nervous system and begin about 10-30 years after syphilis infection.

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