The origin of congenital adrenal hyperplasia occurs when circulating cortisol levels

The origin of congenital adrenal hyperplasia occurs when circulating cortisol levels are low.
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease which results from mutations of genes for enzymes involved in the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroidogenesis). Low cortisol production results in rising levels of ACTH (adrenocorticotropic hormone) because cortisol usually inhibits ACTH production. This increased ACTH production induces overgrowth (hyperplasia) and overactivity of the steroid-producing cells of the adrenal cortex.

By water evaporation from the leaves is created a negative pressure at the top of the tree that promotes the ascension  of the water through channels that are called xylem. there are also two molecule forces that are involved: the intra-water molecules cohesion (water molecules stick to each other) and the adhesion when the water molecules stick to the channels they are running in. this is what enables water to go from the roots to the top of a tall tree.