What is one of the most effective ways that artists create space in two-dimensional art? A) shape
B) line
C) form
D) perspective​

D, perspective

Explanation:

The tools for creating illusions of three dimensional space are overlapping, changing size and placement, linear perspective, relative hue and value, and atmospheric perspective. ... Linear perspective refers to the illusion that objects appear to grow smaller and converge toward a "vanishing point" at the horizon line.

classical and renaissance ideals. he mainly focused in historical paintings, so you could also say that he drew his artistic inspiration from the bible, since he depicted and painted many scenes from it.