Advanced Placement (AP)

A serum cholesterol level above 250 milligrams per deciliter (mg/dl) of blood is a risk factor for cardiovascular disease in humans. At a medical center in St. Louis, a study to test the effectiveness of a new cholesterol lowering drug was conducted. One hundred people with cholesterol levels between 250 mg/dl and 300 mg/dl were available for this study. Fifty people were assigned at random to each of two treatment groups. One group received the standard cholesterol-lowering medication and the other group received the new drug. After taking the drug for three weeks, the 50 subjects who received the standard treatment had a mean decrease in cholesterol level of 10 mg/dl with a standard deviation of 8 mg/dl, and the 50 subjects who received the new drug had a mean decrease of 18 mg/dl with a standard deviation of 12 mg/dl. Does the new drug appear to be more effective than the standard treatment in lowering mean cholesterol level? Give appropriate statistical evidence to support your conclusion.

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